Profile

 

Basic Infomation
Name Hayashi Tetsuya Organization 大学
Name(Japanese) 林 哲也(ハヤシ テツヤ) Major


Education
Start dateEnd dateNameDepartmentDegree
04, 197503, 1981大阪医科大学医学部医学博士
Job(Souai University)
Start dateEnd dateSchool nameOrganizationJobLesson
04, 2021Up to now相愛大学   
Job(Except Souai University)
Start dateEnd dateSchool nameOrganizationJobLesson
12, 198105, 1991大阪医科大学 専攻医・大学院生 
05, 199107, 1993テキサス大学医学部 インストラクター 
07, 199308, 2011大阪医科大学 准教授・治験センター長 
09, 201103, 2021大阪薬科大学 教授 
Lesson (The past three years containing the present fiscal year )
YearTermName
2021First half生化学 (A)
2021First half生化学実験 (B)
2021First half生化学 (B)
2021First half生化学実験 (A)
2021All year管理栄養士演習D
2021Second half疾病の成り立ち (A)
2021Second half管理栄養士演習A
2021Second half食と健康
2021Second half疾病の成り立ち (B)
2022All year卒業研究
2022First half生理学A
2022All year管理栄養士演習D
2022Second half疾病の成り立ち (B)
2022Second half解剖生理学実験 (B)
2022Second half管理栄養士演習A
2022Second half食と健康
2022Second half疾病の成り立ち (A)
2022Second half解剖生理学実験 (A)

Teacher research achievements
Special Field: 動脈硬化症 / 心不全 / 心筋症 / 心臓刺激伝導系 / 睡眠時無呼吸症候群 / 糖尿病性心疾患 / 低酸素ストレス応答
Keyword: 間歇的低酸素負荷 / レニン・アンジオテンシン・アルドステロン系 / 心筋微細構造
The matter about research achievements
Paper
NameCollaborationDateNoteEditorPageOutline
Angiotensin-II receptor blockade prevents microangiopathy and preserve diastolic function in the diabetic rat heart 10, 2003Heart・89・1236〜1242   
Angiotensin-II receptor blocker exerts cardioprotection in diabetic rats exposed to hypoxia 11, 2006Circ J・70・787〜792   
Angiotensin-II receptor blocker reduces oxidative stress and attenuates hypoxia-induced left ventricular remodeling in apolipoprotein E-knockout mice 08, 2007Hypertens Res・30・1219〜1230   
Role of gp91phox-containing NADPH oxidase in left ventricular remodeling induced by intermittent hypoxic stress 06, 2008Am J Physiol-Heart C・294・H2197〜H2203   
Chymase plays an important role in left ventricular remodeling induced by intermittent hypoxia in mice 10, 2009Hypertension・54・164〜171   
Impact of the renin-angiotensin-aldosterone-system on cardiovascular and renal complications in diabetes mellitus 08, 2010Curr Vasc Pharmacol・8・189〜197   
Inhalation of hydrogen gas attenuates left ventricular remodeling induced by intermittent hypoxia in mice 04, 2011Am J Physiol Heart Circ Physiol・301・H1062〜H1069   
Hydrogen gas attenuates embryonic gene expression and prevents left ventricular remodeling induced by intermittent hypoxia in cardiomyopathic hamsters 01, 2014Am J Physiol Heart Circ Physiol・ 307・H1626〜H1633   
Cardiovascular protection by ezetimibe and influence on oxidative stress in mice exposed to intermittent hypoxia 01, 2015Eur J Pharmacol・765・7〜14   
Detection of pharmaceuticals and phytochemicals together with their metabolites in hospital effluents in Japan, and their contribution to sewage treatment plant influents 06, 2016Sci. Total Environ・1・ 548〜549   
Obesity-induced DNA released from adipocytes stimulates chronic adipose tissue inflammation and insulin resistance 06, 2016Science Advance・2・e1501332   
Capillary Degeneration and Right Ventricular Remodeling Due to Hypoxic Stress with Sugen5416 11, 2017Curr Vasc Pharmacol. 15:589〜598   
Factor Xa inhibition by rivaroxaban attenuates cardiac remodeling due to intermittent hypoxia 04, 2018J Pharmacol Sci・137・274〜282   
Dual gas treatment with hydrogen and carbon monoxide attenuates oxidative stress and protects from renal ischemia-reperfusion injury 06, 2018Transplantation Proceedings・50・ 250〜258   
Augmented O-GlcNAcylation attenuates intermittent hypoxia-induced cardiac remodeling through the suppression of NFAT and NF-κB activities in mice 09, 2019Hypertens Res・42・1858〜1871   
The 2-hydroxyiminostilbene metabolite of carbamazepine or the supernatant from incubation of hepatocytes with carbamazepine activates inflammasomes; implications for carbamazepine-induced hypersensitivity reactions 12, 2019Drug Metab Dispos・47・1093〜1096   
Reactive metabolite of gefitinib activates inflammasomes: implications for gefitinib-induced idiosyncratic reaction 10, 2020J Toxicol Sci・45・673〜680J Toxicol Sci・45・673〜680  
Protease-activated receptor-1 inhibition by FR171113 attenuates cardiac remodeling due to intermittent hypoxia 11, 2020Ann Cardiol Vasc Med・3・1036   
Effects of natural sunlight on antimicrobial-resistant bacteria (AMRB) and antimicrobial-susceptible bacteria (AMSB) in wastewater and river waterCollaboration01, 2021Sci Total Environ・766・142568   
Rivaroxaban Attenuates Right Ventricular Remodeling in Rats with Pulmonary Arterial Hypertension 02, 2021Biol Pharm Bull・ 4・669〜677   
Activation of inflammasomes by tyrosine kinase inhibitors of vascular endothelial growth factor receptor: Implications for VEGFR TKIs-induced immune related adverse events 02, 2021Toxicol In Vitro・71・105063   
Amiodarone, unlike Dronedarone, activates inflammasomes via its reactive metabolites: Implications for amiodarone adverse reactions 03, 2021Chem Res Toxicol・ 34・ 1860〜1865   
Disinfection of antibiotic-resistant bacteria in sewage and hospital effluent by ozonation 05, 2021Ozone: Science & Engineering・43・413〜426   
低酸素ストレスとプロテアーゼ活性受容体Single11, 2021YAKUGAKU ZASSHI・141・1195〜1204   
Inactivation of antibiotic-resistant bacteria in wastewater by ozone-based advanced water treatment processes 01, 2022antibiotics・11・210   
Fund acceptance situation
Research fund
Start dateEnd dateItemMoneyOutline
11, 201103, 2013科学研究費補助金 基盤 (C) 間歇的低酸素負荷に伴う臓器別ストレス応答とラジカルスカベンジによる新たな治療戦略(課題番号:23590267)5070000 
07, 201603, 2017Effect of rivaroxaban on atrial and left ventricular remodeling induced by intermittent hypoxia relavant to sleep apnea in mice 3226284 
05, 201703, 2018間歇的低酸素負荷誘導性心血管リモデリングにおけるプロテアーゼ受容体の役割と薬物治療選択300000